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British Hypertension Guidelines Update 1999.
Author: Francisco Machado
Date: 4/11/99
This tutorial is based on a lunchtime presentation at Abersychan Surgery abd should be read in conjuction with the recent BHS guidelines published in the BMJ
To read this document on-line click on the link below.
British
Hypertension Society guidelines for hypertension management 1999: summary BMJ
1999;319:630-635 ( 4 September )
Who wrote the guidelines?
Not a single PHCT professional amongst authors in BMJ article!!
How can these guidelines help us manage patients with hypertension?
Questions I asked when looking at the guidelines
1. How often should patients have their BP measured?
2. How should I measure BP?
Where do the errors occur?
| The patient | The Health Professional | The equipment |
|
|
|
BHS recommendations for BP measurement
3. When should I use ambulatory BP monitoring?
4. How should I assess a patient with hypertension?
History tasks
| Secondary causes of hypertension diabetic nephropathy chronic pyelonephritis obstructive uropathy glomerulonephritis renal artery stenosis -polycystic kidneys |
Lifestyle and risk factors for vascular disease |
Iatrogenic causes |
ICE
Not mentioned in the guidelines but it is very important to elicit the patients
Ideas
Concerns
Expectations
With regard to hypertension and its management.
Examination
| Examine for target organ damage Cardiac
Cerebral
Peripheral vascular disease
Optic
Renal
|
Examine for secondary causes
Cardiovascular Abdominal examination General Condition of patient |
| Investigation of patients In some
|
Management Non pharmacological measures May result in the patient not requiring treatment or a reduction in the dose and number of agents used
Other lifestyle measures to reduce risk of atherosclerosis
|
5. What non-pharmacological measures are effective?
| Management Non pharmacological measures May result in the patient not requiring treatment or a reduction in the dose and number of agents used
Other lifestyle measures to reduce risk of atherosclerosis
|
6. When should I treat and what target levels should I aim for?
For initial blood pressure flow chart click here.
Targets for Blood Pressure.
Measured in Clinic |
Mean daytime ambulatory measurement or home measurement |
|||
| Blood pressure | No Diabetes |
Diabetes |
No diabetes |
Diabetes |
| Optimal | <140/85 |
<140/80 |
<130/80 |
<130/75 |
| Audit standard | <150/90 |
<140/85 |
<140/85 |
<140/80 |
7.Which drug should I use?
Which drugs to use first?
| Class of drug | Indication |
Contraindications |
||
| Compelling | Possible | Possible | Compelling | |
| Alpha blockers | Prostatism | Dyslipidaemia | Postural hypotension | Urinary Incontinence |
| ACE inhibitors | Heart Failure LV dysfunction Type 1 diabetic nephropathy |
Chronic renal disease Type II diabetic nephropathy |
Renal impairment Peripheral vascular disease |
Pregnancy Renovascular disease |
| Angiotensin II receptor antagonists | Cough induced by ACEI | Heart failure Intolerance of other antihypertensive drugs |
Peripheral vascular disease | Pregnancy Renovascular disease |
| Beta blockers | Myocardial infarction Angina |
??Heart failure | ??Heart failure Dyslipidaemia Peripheral vascular disease |
Asthma or COPD Heart block |
| Calcium antagonists (dihydropyridine) |
Isolated systolic hypertension in elderly | Angina Elderly |
||
| Calcium antagonists (rate limiting) |
Angina | Myocardial infarction | Combination with beta blocker | Heart block Heart Failure |
| Thiazides | Elderly | Dyslipidaemia | Gout | |
8.How should I use these drugs?
Rational combinations
beta -blockers and diureticsCambridge AB/CD rule for optimisation of antihypertensive treatment
| Age | Young |
Old |
| Renin levels | High |
Low |
| Absolute risk reduction | Low |
High |
| Relative risk reduction | High |
Low |
| Step 1 mono-therapy | A or B |
C or D |
| Step 2 mono-therapy | C or D |
A or B |
| Step 3 combination | A or B + C or D |
A or B + C or D |
| Resistant hypertension/Intolerance | Add/substitute alpha blocker |
Add/substitute alpha blocker |
A = ACEI, B = beta-blocker, C = Calcium antagonist, D = Diuretic
Dickerson JEC, Hingorani AD, Ashley MJ et al. Optimisation of antihypertensive treatment by crossover rotation of four major classes. Lancet 1999; 353: 2008-13
9. Are there any special groups?
Elderly
>50% of all people > 60 ð >160/90
More to gain from treatment
Evidence to 80years of age
Diabetics
Pregnancy
10.When should I refer?
11. What about statins and aspirin?
Primary prevention 75mg aspirin is recommended for hypertensive patients aged > 50 who have satisfactory control of BP and either target organ damage, diabetes or a 10 year coronary risk > 15
For primary prevention, statin therapy is indicated up to the age of 70 when serum total CE > 5.0 mmol/l and the 10 year coronary heart disease risk is > 30
For secondary prevention of coronary heart disease statin therapy is indicated up to 75 years if total CE is > 5.0mmol/l and aspirin is indicated (75mg)
12. How should patients be followed up?
Routine
3/12
13. What about a protocol?
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